eLife1d
Xist RNA binds select autosomal genes and depends on Repeat B to regulate their expression
This valuable study addresses potential roles of the master regulator of X chromosome inactivation, the Xist long non-coding RNA, in autosomal gene regulation. Using data from mouse cells, the authors ...
eLife3d
Rabphilin-3A negatively regulates neuropeptide release, through its SNAP25 interaction
Live imaging at single-vesicle resolution reveals rabphilin-3A as the first identified negative regulator of neuropeptide release in mammalian neurons.
eLife5d
A host enzyme reduces non-alcoholic fatty liver disease by inactivating intestinal lipopolysaccharide
The findings are significant for the liver research community and others interested in the gut-liver axis. (A) AOAH cleaves the two piggyback fatty acyl chains from the lipid A moiety, inactivating ...
eLife3d
Range geographies, not functional traits, explain convergent range and phenology shifts under climate change
This article presents valuable findings on the impact of climate change on odonates, integrating phenological and range shifts to broaden our understanding of biodiversity change. The study leverages ...
eLife3d
Vole Parenting: A fine line between attack and care
Oxytocin neuron projections from two brain regions involved in parental care regulate both parental care and infanticidal behaviors in virgin mandarin voles.
eLife3d
Hypothalamic representation of the imminence of predator threat detected by the vomeronasal organ in mice
A molecular genetics study reveals an accessory olfactory-to-hypothalamic circuit in mice that optimizes defensive behaviors according to the imminence of predator threats.
eLife3d
Loss function of tumor suppressor FRMD8 confers resistance to tamoxifen therapy via a dual mechanism
Program for Cancer and Cell Biology, Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences; Peking University International Cancer Institute; and State Key Laboratory ...
eLife4d
Amidase and Lysozyme Dual Functions in TseP Reveal a New Family of Chimeric Effectors in the Type VI Secretion System
State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, ...
eLife5d
Prediction tendency, eye movements, and attention in a unified framework of neural speech tracking
These are valuable findings for those interested in how neural signals reflect auditory speech streams, and in understanding the roles of prediction, attention, and eye movements in this tracking.
eLife4d
Arthropods dominate plant litter decomposition in drylands
An analysis of leaf litter breakdown in climatically diverse habitats shows that decomposition by larger invertebrates dominates in hot, dry regions and warmer seasons.
eLife5d
Group identification drives brain integration for collective performance
Shanghai Key Laboratory of Mental Health and Psychological Crisis Intervention, Affiliated Mental Health Center (ECNU), School of Psychology and Cognitive Science, East China Normal University, ...
eLife4d
Reconstructing the evolutionary history of freshwater fishes (Nemacheilidae) across Eurasia since early Eocene
Series of paleomaps visualising the geographical and chronological aspects of the main events during the evolutionary history of the freshwater fish family Nemacheilidae across Eurasia. A red star ...